![]() ![]() There they mate, lay their eggs and die, fulfilling their duty, after an arduous journey of life. Once they are grown and ready, they leave liver, their journey bound to intestine or the urinary bladder, traveling against the bloody deluge of portal circulation, seeking their destination – the warm, cozy venous plexus of the urinary bladder. There they take shelter for 2–3 weeks, growing in the safe confinement of portal blood, in disguise of host antigen, avoiding the army of human immunity. Finally, when they meet the skin of a person swimming or waddling, they lose their tail, form little schistosomes, drill through the skin, pass through lymph or blood and reach liver. They keep swimming, up and down the lake, in wait for the last, but most difficult and important part of their journey – human body. They then penetrate the body of an unsuspecting snail, inside which they grow silently and come out as the fork tailed cercariae. There the eggs hatch, releasing the hairy, free-swimming larvae, known as the miracidia. It all begins when the tiny fluke eggs are released into the freedom of a freshwater from the confines of the salty human pee. It has a riveting history and a fascinating life cycle, making it one of the most alluring among the parasitic worms. ![]() One of the most interesting genre in the field of parasitology is the flukes, and the blood fluke Schistosoma holds a special place. 4 The Tiny Worm that beat the Mighty Emperor ![]()
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